SCHEMBL22133451

SCHEMBL22133451

C=C/C=C(C)\C=C\Nc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.47
RAB9A P51151 11/20 0.47
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 6/20 0.47
NPSR1 Q6W5P4 2/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
MAPT P10636 7/20 0.39
PKM P14618 4/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GAA P10253 3/20 0.39
MAPK1 P28482 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TP53 P04637 2/20 0.39
ALOX15 P16050 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23191752 0.81 NPC1 (0.53) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL24731361 0.78 RAB9A (0.44) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL24971332 0.77 NPC1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL16252099 0.77 NPC1 (0.53) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL13790518 0.77 KMT2A (0.55) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL10064564 0.77 KMT2A (0.55) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL3910252 0.76 KMT2A (0.54) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL18773856 0.74 NPC1 (0.42) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL21479798 0.73 NPC1 (0.53) NPC1RAB9AALDH1A1SMN1; SMN2NPSR1
SCHEMBL25665 0.72 GLA (0.53) NPC1ALDH1A1SMN1; SMN2NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020130664-A1 ORGANIC LUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE USING SAME 두산솔루스 주식회사 2020-06-25 WO disclosed