Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.41 |
| ▸ | NMT2 | O60551 | 4/20 | 0.41 |
| ▸ | FURIN | P09958 | 6/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860132 | 1.00 | NMT1 (0.41) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL20287670 | 1.00 | NMT1 (0.41) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL24993722 | 0.98 | FURIN (0.42) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL21972921 | 0.90 | NMT1 (0.40) | NMT1NMT2TLR2ROCK2PRKACA | |
| SCHEMBL17860164 | 0.89 | HRH1 (0.39) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL22134316 | 0.89 | HRH1 (0.39) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL20287648 | 0.89 | HRH1 (0.39) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL17860183 | 0.88 | NMT2 (0.40) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL20349812 | 0.87 | NMT2 (0.39) | NMT1NMT2FURINPRSS1CTSL | |
| SCHEMBL19776913 | 0.87 | NMT2 (0.39) | NMT1NMT2FURINPRSS1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3086814-B1 | DRUG CONJUGATES (ADCS) WITH KINESIN SPINDEL PROTEIN (KSP) | Bayer Pharma AG (DE) | 2020-06-24 | — | — | EP | disclosed |