Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437497 | 0.97 | STING1 (0.68) | STING1CYP3A4 | |
| SCHEMBL22857820 | 0.94 | STING1 (0.59) | STING1CYP3A4 | |
| SCHEMBL19437498 | 0.87 | STING1 (0.53) | STING1 | |
| SCHEMBL25098724 | 0.87 | STING1 (0.68) | STING1CYP3A4 | |
| SCHEMBL30206995 | 0.87 | STING1 (0.68) | STING1CYP3A4 | |
| SCHEMBL22857865 | 0.86 | STING1 (0.58) | STING1CYP3A4 | |
| SCHEMBL22857879 | 0.84 | STING1 (0.70) | STING1CYP3A4 | |
| SCHEMBL22857886 | 0.83 | STING1 (0.55) | STING1CYP3A4 | |
| SCHEMBL22925517 | 0.83 | STING1 (0.65) | STING1CYP3A4 | |
| SCHEMBL22121522 | 0.83 | STING1 (0.65) | STING1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |