Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925517 | 1.00 | STING1 (0.65) | STING1CYP3A4 | |
| SCHEMBL26772068 | 0.93 | STING1 (0.57) | STING1CYP3A4 | |
| Bromide SCHEMBL30615794 | 0.92 | STING1 (0.56) | STING1CYP3A4 | |
| Bromide SCHEMBL29791230 | 0.92 | STING1 (0.56) | STING1CYP3A4 | |
| Bromide SCHEMBL29080462 | 0.92 | STING1 (0.56) | STING1CYP3A4 | |
| SCHEMBL23077541 | 0.90 | STING1 (0.57) | STING1CYP3A4 | |
| SCHEMBL29437070 | 0.89 | STING1 (0.54) | STING1CYP3A4 | |
| SCHEMBL23095398 | 0.89 | STING1 (0.54) | STING1CYP3A4 | |
| SCHEMBL21643887 | 0.89 | STING1 (0.54) | STING1CYP3A4 | |
| SCHEMBL22121231 | 0.89 | STING1 (0.54) | STING1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585623-A | Bis [ N- ((5-carbamoyl) -1H-benzo [ d ] imidazol-2-yl) pyrazole-5-carboxamide ] derivatives and related compounds as STING (interferon gene stimulator) agonists for the treatment of cancer | 梅尔莎纳医疗公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |