Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19016204 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL18288374 | 0.80 | CA12 (0.41) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL18288192 | 0.80 | CA12 (0.41) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL22135133 | 0.78 | CA12 (0.39) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL22135146 | 0.78 | CA12 (0.39) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL19016210 | 0.78 | CA12 (0.43) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL18288343 | 0.75 | CA12 (0.37) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL10665490 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL20319858 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2CA12CA1CA9CA2 | |
| SCHEMBL8557483 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2CA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020128964-A2 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-06-25 | — | — | WO | disclosed |