Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18288374 | 1.00 | CA12 (0.41) | CA12CA1CA9CA2MGLL | |
| SCHEMBL22135147 | 0.80 | SMN1; SMN2 (0.44) | CA12CA1CA9CA2MGLL | |
| SCHEMBL19016204 | 0.80 | SMN1; SMN2 (0.44) | CA12CA1CA9CA2MGLL | |
| SCHEMBL22135146 | 0.78 | CA12 (0.39) | CA12CA1CA9CA2MGLL | |
| SCHEMBL22135133 | 0.78 | CA12 (0.39) | CA12CA1CA9CA2MGLL | |
| SCHEMBL19016210 | 0.78 | CA12 (0.43) | CA12CA1CA9CA2MGLL | |
| SCHEMBL20319196 | 0.77 | CA12 (0.42) | CA12CA1CA9CA2MGLL | |
| SCHEMBL18288191 | 0.76 | — | — | |
| SCHEMBL18288343 | 0.75 | CA12 (0.37) | CA12CA1CA9CA2MGLL | |
| SCHEMBL19343687 | 0.74 | ALDH1A1 (0.38) | CA12CA1CA9CA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303435-B1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3390464-B1 | AQUEOUS DISPERSIONS OF AMINE-CONTAINING FLUORINATED POLYMERS AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2020-10-21 | — | — | EP | disclosed |
| US-10738001-B2 | Hydrofluoroolefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-08-11 | — | — | US | disclosed |
| US-10344006-B2 | Amine-containing acyclic hydrofluoroethers and methods of using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-07-09 | — | — | US | disclosed |
| US-10301293-B2 | Amine-containing cyclic hydrofluoroethers and methods of using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190040024-A1 | AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-02-07 | — | — | US | disclosed |
| US-20190031646-A1 | AMINE-CONTAINING CYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2019-01-31 | — | — | US | disclosed |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
| WO-2017155686-A1 | AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017155735-A1 | AMINE-CONTAINING CYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2016196240-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301293-B2 | Amine-containing cyclic hydrofluoroethers and methods of using the same | AFF2, AFF1, AFF4 | CA12 729/4885CA1 765/4885CA9 801/4885 |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | RFC3, RFC2, RFC1 | CA12 1746/4885CA1 2229/4885CA9 3510/4885 |
| US-10344006-B2 | Amine-containing acyclic hydrofluoroethers and methods of using the same | AFF1, AFF2, FANCF | CA12 718/4885CA1 193/4885CA9 1277/4885 |
| US-10738001-B2 | Hydrofluoroolefins and methods of using same | RFC3, RFC2, RFC1 | CA12 1746/4885CA1 2229/4885CA9 3510/4885 |
| US-20190040024-A1 | AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | AFF1, AFF2, FANCF | CA12 718/4885CA1 193/4885CA9 1277/4885 |
| US-20190031646-A1 | AMINE-CONTAINING CYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | AFF2, AFF1, AFF4 | CA12 729/4885CA1 765/4885CA9 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.