SCHEMBL22135310

SCHEMBL22135310

COc1cc(C(N)=O)cc2nc(N)n(CCCNC3CCC3)c12

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19437498 0.84 STING1 (0.53) STING1
SCHEMBL19437481 0.82 STING1 (0.59) STING1
SCHEMBL22135036 0.82 STING1 (0.49) STING1
SCHEMBL19437508 0.81 STING1 (0.55) STING1
SCHEMBL29692138 0.80 STING1 (0.57) STING1
SCHEMBL19437504 0.80 STING1 (0.57) STING1
SCHEMBL22135028 0.80 STING1 (0.64) STING1
SCHEMBL28515124 0.79 STING1 (0.47) STING1
SCHEMBL19437494 0.79 STING1 (0.49) STING1
SCHEMBL28508303 0.79 STING1 (0.47) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 — — WO disclosed
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