Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118804 | 0.91 | GAA (0.58) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL22428322 | 0.91 | PRSS1 (0.71) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL29512975 | 0.91 | PRSS1 (0.71) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL22908881 | 0.91 | PRSS1 (0.71) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL29513036 | 0.91 | PRSS1 (0.71) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL9525197 | 0.88 | KDM4E (0.72) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL22908891 | 0.87 | PRSS1 (0.69) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL31494211 | 0.84 | GAA (0.74) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL11232662 | 0.83 | ALDH1A1 (0.54) | PRSS1PTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL19436451 | 0.82 | PRSS1 (0.60) | PRSS1PTGER4GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |