SCHEMBL22135337

SCHEMBL22135337

CCN/C(=C\C(=N)C(F)(F)F)C(=O)Nc1nc2cc(C(N)=O)cc(OC)c2n1CCCNC

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22135039 0.83 STING1 (0.49) STING1
SCHEMBL22135328 0.79 STING1 (0.51) STING1
SCHEMBL25827513 0.72 STING1 (0.43) STING1
SCHEMBL22135346 0.72 STING1 (0.86) STING1
SCHEMBL24467518 0.72 STING1 (0.66) STING1
SCHEMBL27388052 0.70 STING1 (0.45) STING1
SCHEMBL19448954 0.70 STING1 (0.62) STING1
SCHEMBL22136003 0.70 STING1 (0.66) STING1
SCHEMBL19451577 0.69 STING1 (0.62) STING1
SCHEMBL22136233 0.69 STING1 (0.68) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132566-A1 STING PYRAZOLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed