Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SCN4A | P35499 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015785 | 0.91 | KDM4E (0.56) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL8347835 | 0.90 | KDM4E (0.59) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL11096244 | 0.89 | KDM4E (0.55) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL25261375 | 0.89 | KDM4E (0.61) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL8234481 | 0.88 | KDM4E (0.56) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL8295970 | 0.86 | KDM4E (0.59) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL3525710 | 0.86 | ALDH1A1 (0.57) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL26758033 | 0.86 | KDM4E (0.55) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL5074470 | 0.85 | KDM4E (0.66) | KDM4ETP53ALOX15ALDH1A1MEN1 | |
| SCHEMBL20005629 | 0.85 | SCN4A (0.55) | KDM4ETP53ALOX15ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185494-A1 | BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020132244-A1 | BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020131566-A1 | BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-06-25 | — | — | WO | disclosed |