SCHEMBL22136104

SCHEMBL22136104

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc(-c5ccc6ccc7ncccc7c6c5)cc5c4sc4ccccc45)c3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
MAPK10 P53779 1/20 0.37
ALOX5 P09917 1/20 0.37
ACVR1 Q04771 4/20 0.36
PIK3CA P42336 1/20 0.35
DYRK1B Q9Y463 1/20 0.33
MAPT P10636 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
LIMK1 P53667 1/20 0.33
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DYRK1A Q13627 2/20 0.32
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MMP1 P03956 1/20 0.32
MMP9 P14780 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22136058 0.95 CYP3A4 (0.41) CYP3A4MAPK10ALOX5ACVR1PIK3CA
SCHEMBL22136331 0.93 CYP3A4 (0.41) CYP3A4MAPK10ALOX5ACVR1PIK3CA
SCHEMBL22135985 0.92 MAPK10 (0.40) CYP3A4MAPK10ALOX5ACVR1PIK3CA
SCHEMBL22136055 0.90 ALOX5 (0.38) CYP3A4MAPK10ALOX5PIK3CAMAPT
SCHEMBL22136098 0.88 ALOX5 (0.37) CYP3A4ALOX5PIK3CAMAPTNPC1
SCHEMBL22136327 0.87 MAPK10 (0.38) CYP3A4MAPK10PIK3CAMAPTNPC1
SCHEMBL22136192 0.87 ALOX5 (0.36) CYP3A4ALOX5ACVR1PIK3CAMAPT
SCHEMBL22136097 0.86 ALOX5 (0.38) MAPK10ALOX5PIK3CAMAPTNPC1
SCHEMBL22136095 0.86 MAPK10 (0.46) CYP3A4MAPK10ALOX5PIK3CAMAPT
SCHEMBL17425450 0.85 ALOX5 (0.46) ALOX5MAPTLIMK1LMNATNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020130553-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 두산솔루스 주식회사 2020-06-25 WO disclosed