SCHEMBL22136128

SCHEMBL22136128

CCc1nn(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OC)c2n1CCCNC(=O)OC1CCCC1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22136277 0.86 STING1 (0.56) STING1
SCHEMBL22135936 0.85 STING1 (0.54) STING1
SCHEMBL22135937 0.84 STING1 (0.54) STING1
SCHEMBL22136247 0.84 STING1 (0.73) STING1
SCHEMBL22136004 0.83 STING1 (0.55) STING1
SCHEMBL22136243 0.83 STING1 (0.73) STING1
SCHEMBL22135998 0.83 STING1 (0.55) STING1
SCHEMBL22136123 0.82 STING1 (0.54) STING1
SCHEMBL22135222 0.78 STING1 (0.73) STING1
SCHEMBL22135228 0.78 STING1 (0.73) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132549-A1 STING HETEROCYCLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed