SCHEMBL22136243

SCHEMBL22136243

CCCn1c(NC(=O)c2cn(C)nc2CC)nc2cc(C(N)=O)cc(OC)c21

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29686412 0.85 STING1 (1.00) STING1
SCHEMBL28752044 0.85 STING1 (1.00) STING1
SCHEMBL22933977 0.85 STING1 (1.00) STING1
SCHEMBL22136247 0.83 STING1 (0.73) STING1
SCHEMBL22136128 0.83 STING1 (0.61) STING1
SCHEMBL22136001 0.83 STING1 (0.73) STING1
SCHEMBL22136233 0.82 STING1 (0.68) STING1
SCHEMBL22135963 0.81 STING1 (0.65) STING1
SCHEMBL22136003 0.81 STING1 (0.66) STING1
SCHEMBL19449040 0.81 STING1 (1.00) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132549-A1 STING HETEROCYCLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed