Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.54 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136142 | 0.83 | STING1 (0.58) | STING1TBK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22135934 | 0.82 | STING1 (0.53) | STING1TBK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22136139 | 0.82 | STING1 (0.53) | STING1TBK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22135963 | 0.81 | STING1 (0.65) | STING1TBK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22135933 | 0.80 | BACE1 (0.48) | STING1TBK1EHMT2EHMT1 | |
| SCHEMBL22136125 | 0.78 | STING1 (0.47) | STING1TBK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22136247 | 0.74 | STING1 (0.73) | STING1 | |
| SCHEMBL22136265 | 0.73 | STING1 (0.55) | STING1TBK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22151356 | 0.72 | STING1 (0.62) | STING1TBK1 | |
| SCHEMBL22136274 | 0.71 | STING1 (0.61) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |