Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135934 | 0.84 | STING1 (0.53) | STING1TBK1EHMT2EHMT1ITK | |
| SCHEMBL22135908 | 0.82 | STING1 (0.56) | STING1TBK1ITKCYP2C19 | |
| SCHEMBL22136253 | 0.80 | STING1 (0.50) | STING1TBK1EHMT2EHMT1CYP3A4 | |
| SCHEMBL22136142 | 0.79 | STING1 (0.58) | STING1TBK1EHMT2EHMT1ITK | |
| SCHEMBL22136131 | 0.78 | STING1 (0.54) | STING1TBK1EHMT2EHMT1ITK | |
| SCHEMBL22136139 | 0.78 | STING1 (0.53) | STING1TBK1EHMT2EHMT1ITK | |
| SCHEMBL22135933 | 0.78 | BACE1 (0.48) | STING1TBK1EHMT2EHMT1 | |
| SCHEMBL22118179 | 0.76 | STING1 (0.69) | STING1 | |
| SCHEMBL22135941 | 0.75 | MAP3K7 (0.53) | STING1TBK1CYP2C19 | |
| SCHEMBL22136283 | 0.73 | KDM4E (0.59) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |