Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 10/20 | 0.61 |
| ▸ | ITK | Q08881 | 3/20 | 0.59 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.58 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136145 | 0.82 | ITK (0.61) | STING1ITKMAP3K7TBK1KDM4E | |
| SCHEMBL22118178 | 0.81 | STING1 (0.66) | STING1MAP3K7TBK1KDM4EKMT2A | |
| SCHEMBL22135923 | 0.81 | MAP3K7 (0.62) | STING1ITKMAP3K7TBK1KDM4E | |
| SCHEMBL22136256 | 0.80 | STING1 (0.61) | STING1ITKMAP3K7TBK1KDM4E | |
| SCHEMBL22136152 | 0.80 | STING1 (0.65) | STING1MAP3K7TBK1KDM4EKMT2A | |
| SCHEMBL22135964 | 0.79 | STING1 (0.62) | STING1ITKINSRMAP3K7TBK1 | |
| SCHEMBL22136149 | 0.79 | STING1 (0.64) | STING1MAP3K7TBK1KDM4EKMT2A | |
| SCHEMBL22135981 | 0.78 | STING1 (0.64) | STING1MAP3K7TBK1KDM4EKMT2A | |
| SCHEMBL22135356 | 0.78 | STING1 (0.68) | STING1MAP3K7TBK1KDM4EKMT2A | |
| SCHEMBL22135904 | 0.77 | STING1 (0.62) | STING1ITKMAP3K7TBK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |