Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 7/20 | 0.65 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.58 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.58 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118178 | 0.89 | STING1 (0.66) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22135906 | 0.89 | STING1 (0.61) | STING1MAP3K7NPSR1SAE1UBA2 | |
| SCHEMBL22136149 | 0.87 | STING1 (0.64) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22135975 | 0.86 | STING1 (0.61) | STING1MAP3K7TBK1KMT2AKDM4E | |
| SCHEMBL22135904 | 0.85 | STING1 (0.62) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22136148 | 0.84 | STING1 (0.61) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22136297 | 0.83 | STING1 (0.59) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22135356 | 0.82 | STING1 (0.68) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22135907 | 0.82 | STING1 (0.58) | STING1MAP3K7NPSR1TBK1KMT2A | |
| SCHEMBL22136236 | 0.81 | POLB (0.60) | STING1KMT2AMEN1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |