Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 18/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.51 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136265 | 0.92 | STING1 (0.55) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22135935 | 0.91 | STING1 (0.51) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22135934 | 0.87 | STING1 (0.53) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22136006 | 0.86 | STING1 (0.76) | STING1 | |
| SCHEMBL22119610 | 0.83 | STING1 (0.79) | STING1 | |
| SCHEMBL22151647 | 0.82 | STING1 (0.62) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22119105 | 0.81 | STING1 (0.53) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22136287 | 0.81 | STING1 (0.65) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22136264 | 0.80 | STING1 (0.60) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22135909 | 0.74 | STING1 (0.61) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |