Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288523 | 0.86 | PTGES (0.61) | LTB4R2TMEM97SIGMAR1TSHRHTT | |
| SCHEMBL11169998 | 0.85 | NAMPT (0.49) | NPC1RAB9ALTB4R2TSHRHTT | |
| SCHEMBL22135045 | 0.84 | NPC1 (0.51) | NPC1RAB9ACA12CA9ABCC1 | |
| SCHEMBL967460 | 0.83 | NPC1 (0.62) | NPC1RAB9ACA12CA9ABCC1 | |
| SCHEMBL23978704 | 0.83 | NPC1 (0.57) | NPC1RAB9ACA12CA9ABCC1 | |
| SCHEMBL24803427 | 0.83 | NPC1 (0.57) | NPC1RAB9ACA12CA9ABCC1 | |
| SCHEMBL3483294 | 0.81 | PTGES (0.53) | LTB4R2TMEM97SIGMAR1TSHRHTT | |
| SCHEMBL23686835 | 0.80 | NPC1 (0.62) | NPC1RAB9ACA12CA9ABCC1 | |
| SCHEMBL29221801 | 0.80 | PTGES (0.59) | TMEM97SIGMAR1HTTHPGD | |
| SCHEMBL12582517 | 0.80 | LTB4R2 (0.65) | NPC1RAB9ALTB4R2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |