SCHEMBL22136179

SCHEMBL22136179

CCCCNC(=O)OC1CCCCCC1

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 11/20 0.69
GAA P10253 1/20 0.61
NAAA Q02083 3/20 0.54
BCHE P06276 1/20 0.54
ACHE P22303 1/20 0.50
EPHX2 P34913 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2801495 1.00 EPHX1 (0.69) EPHX1GAANAAABCHEACHE
SCHEMBL22134964 0.98 EPHX1 (0.66) EPHX1GAANAAABCHEACHE
SCHEMBL12991745 0.95 EPHX1 (0.67) EPHX1GAANAAABCHEEPHX2
SCHEMBL8243750 0.95 GAA (0.63) EPHX1GAANAAABCHEACHE
SCHEMBL21059247 0.93 EPHX1 (0.65) EPHX1GAANAAAEPHX2
SCHEMBL15975473 0.93 EPHX1 (0.65) EPHX1GAANAAAEPHX2
SCHEMBL16374741 0.93 EPHX1 (0.64) EPHX1GAANAAABCHEEPHX2
SCHEMBL14703637 0.92 EPHX1 (0.62) EPHX1GAANAAAEPHX2
SCHEMBL14424470 0.89 EPHX1 (0.73) EPHX1GAANAAABCHE
SCHEMBL23200480 0.87 EPHX1 (0.70) EPHX1GAANAAABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132549-A1 STING HETEROCYCLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed