SCHEMBL8243750

SCHEMBL8243750

CCCCNC(=O)OC1CCC1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.63
EPHX1 P07099 4/20 0.61
BCHE P06276 2/20 0.55
ACHE P22303 8/20 0.52
NAAA Q02083 2/20 0.49
KCNA3 P22001 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22134964 0.96 EPHX1 (0.66) GAAEPHX1BCHEACHENAAA
SCHEMBL22136179 0.95 EPHX1 (0.69) GAAEPHX1BCHEACHENAAA
SCHEMBL2801495 0.95 EPHX1 (0.69) GAAEPHX1BCHEACHENAAA
SCHEMBL16374741 0.91 EPHX1 (0.64) GAAEPHX1BCHENAAA
SCHEMBL12991745 0.90 EPHX1 (0.67) GAAEPHX1BCHENAAA
SCHEMBL14703637 0.90 EPHX1 (0.62) GAAEPHX1NAAA
SCHEMBL20928290 0.89 EPHX1 (0.65) GAAEPHX1BCHENAAAKCNA3
SCHEMBL21059247 0.88 EPHX1 (0.65) GAAEPHX1NAAA
SCHEMBL15975473 0.88 EPHX1 (0.65) GAAEPHX1NAAA
SCHEMBL24263885 0.88 GAA (0.58) GAAEPHX1BCHEACHENAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022125904-A1 ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-06-16 WO disclosed
WO-2022125915-A1 ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-06-16 WO disclosed
WO-2022125908-A1 ANTI-PD-L1 IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-06-16 WO disclosed
WO-2022125884-A1 IMMUNOCONJUGATES COMPRISING AN ANTI-CEA ANTIBODY LINKED BY CONJUGATION TO ONE OR|MORE 8-HET-2- AMINOBENZAZEPINE DERIVATIVES USEFUL IN TREATING CANCER BOLT BIOTHERAPEUTICS, INC. (US) 2022-06-16 WO disclosed
WO-2022125891-A2 ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-06-16 WO disclosed
CN-102264710-B Cysteine protease inhibitors MEDIVIR UK LTD 2014-11-05 CN disclosed
US-20040229818-A1 Hepatitis C inhibitor compound BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229818-A1 Hepatitis C inhibitor compound HAVCR2, GTF3C1, RNASE1 GAA 1146/4885EPHX1 1187/4885BCHE 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.