Valine

Valine

SCHEMBL2213629

CC(C)[C@H](N)C(=O)O.NC(N)=O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.88
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
SLC1A1 P43005 2/20 0.44
TP53 P04637 1/20 0.40
DPP4 P27487 1/20 0.38
FAP Q12884 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
DPP7 Q9UHL4 1/20 0.38
LAP3 P28838 1/20 0.38
ACHE P22303 1/20 0.37
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GABRP O00591 3/20 0.35
GABRD O14764 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL756026 0.94 SLC7A5 (0.88) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Valine SCHEMBL296920 0.94 SLC7A5 (0.88) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Valine SCHEMBL935768 0.94 SLC7A5 (0.88) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Valine SCHEMBL41225 0.94 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Valine SCHEMBL43678 0.94
Valine SCHEMBL1813972 0.94 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Valine SCHEMBL8516 0.94
Valine SCHEMBL2785563 0.94 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Valine SCHEMBL8515 0.94
Valine SCHEMBL288203 0.94 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110205067-B Environment-friendly urea-formaldehyde resin adhesive and preparation method and application thereof 厦门大学 2020-11-10 CN claimed
CN-110205067-A A kind of environment protection type urea formaldehyde resin adhesive and its preparation method and application 厦门大学 2019-09-06 CN claimed
CN-117839616-A Accurate reloading of sorbent materials using patient and session data 美敦力公司 2024-04-09 CN disclosed
CN-117142884-A Use of polysuccinimide, synergistic urea composition for improving urea processing and preparation method thereof 呼伦贝尔金新化工有限公司 2023-12-01 CN disclosed
CN-117142885-A Synergistic urea and its preparation method 呼伦贝尔金新化工有限公司 2023-12-01 CN disclosed
CN-114956898-B Nitrogen fixation fertilizer retention synergist, self-assembled nitrogen-containing fertilizer containing nitrogen fixation fertilizer retention synergist and preparation method 河北协同化学有限公司 2023-10-13 CN disclosed
CN-112778328-B N-heterocyclic carbene catalytic functionalized imine as novel 1, 4-dipole synthesizer and synthesis application thereof 南京工业大学 2023-05-26 CN disclosed
CN-110812555-B Method and system for precision dialysis treatment based on sorbent effluent analysis 美敦力公司 2023-03-14 CN disclosed
US-20230015914-A1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. 2023-01-19 US disclosed
CN-114956898-A Nitrogen-fixing fertilizer-maintaining synergist, self-assembly nitrogen-containing fertilizer containing nitrogen-fixing fertilizer-maintaining synergist and preparation method of self-assembly nitrogen-containing fertilizer 河北协同化学有限公司 2022-08-30 CN disclosed
WO-2021015571-A1 TRANSGENIC CLONED PIG FOR XENOTRANSPLANTATION EXPRESSING HUMAN CD46 AND TBM GENES, IN WHICH PORCINE ENDOGENOUS RETROVIRUS ENVELOPE C IS NEGATIVE AND GGTA1, CMAH, IGB3S AND β4GALNT2 GENES ARE KNOCKED OUT, AND METHOD FOR PREPARING SAME 주식회사 옵티팜 2021-01-28 WO disclosed
US-6090250-A CAPILLARY ELECTROPHORESIS CHROMATOGRAPHY USING AN ANIONIC SURFACTANT HAVING A HYDROPHOBIC TAIL IN A CHANNEL WITH AN ELECTROLYTE SOLUTION WHERE THE COMPOUND, E.G., ASPARTAME, IS INJECTED, VOLTAGE APPLIED AND MICELLES FORMED; HIGH SPEED WATERS INVESTMENTS LIMITED (US) 2000-07-18 US disclosed
EP-0973719-A4 METHOD OF PREPARING AMINO CARBOXYLIC ACIDS MONSANTO CO (US) 2000-05-17 EP disclosed
EP-0973719-A1 METHOD OF PREPARING AMINO CARBOXYLIC ACIDS MONSANTO COMPANY (US) 2000-01-26 EP disclosed
CN-1239473-A Method of preparing amino carboxylic acids MONSANTO CO (US) 1999-12-22 CN disclosed
WO-1998035930-A1 METHOD OF PREPARING AMINO CARBOXYLIC ACIDS MONSANTO COMPANY (US) 1998-08-20 WO disclosed
EP-0721446-A1 CHIRAL SURFACTANTS AND METHODS FOR THEIR USE IN CHIRAL SEPARATIONS Waters Corporation (US) 1996-07-17 EP disclosed
WO-1995008529-A1 CHIRAL SURFACTANTS AND METHODS FOR THEIR USE IN CHIRAL SEPARATIONS WATERS CORPORATION (US) 1995-03-30 WO disclosed
US-4826975-A HYPOTENSIVE, ANTICOAGULANT, ANTILIPEMIC MAGGIONI-WINTHROP S.P.A. (IT) 1989-05-02 US disclosed
WO-1987002035-A1 FUSED CYCLOALIPHATIC AMINOALCOHOLS MAGGIONI-WINTHROP S.P.A. (IT) 1987-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230015914-A1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF MC3R, MC1R, MC2R SLC7A5 3297/4885SLC1A3 1795/4885SLC1A2 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.