Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 14/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136238 | 0.86 | STING1 (0.62) | STING1 | |
| SCHEMBL21158748 | 0.84 | STING1 (0.61) | STING1 | |
| SCHEMBL21158740 | 0.84 | STING1 (0.86) | STING1 | |
| SCHEMBL21158741 | 0.83 | STING1 (0.59) | STING1 | |
| SCHEMBL22136003 | 0.81 | STING1 (0.66) | STING1 | |
| SCHEMBL21158754 | 0.79 | STING1 (0.89) | STING1 | |
| SCHEMBL21158978 | 0.77 | STING1 (0.51) | STING1 | |
| SCHEMBL22857830 | 0.76 | STING1 (0.46) | STING1 | |
| SCHEMBL19448954 | 0.76 | STING1 (0.62) | STING1 | |
| SCHEMBL22136233 | 0.72 | STING1 (0.68) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |