Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611855 | 1.00 | ALK (0.42) | ALKSIRT2SIRT1ALDH1A1CYP3A4 | |
| SCHEMBL5493498 | 0.97 | ALK (0.40) | ALKSIRT2SIRT1ALDH1A1CYP3A4 | |
| SCHEMBL2210750 | 0.95 | ALDH1A1 (0.39) | ALKSIRT2SIRT1ALDH1A1CYP3A4 | |
| SCHEMBL14461554 | 0.88 | ALK (0.50) | ALKSIRT2SIRT1ALDH1A1CYP3A4 | |
| SCHEMBL13260855 | 0.88 | HPGD (0.42) | EGFRMAPKAPK2MAPTTDP1KDM4E | |
| SCHEMBL4806069 | 0.88 | ALDH1A1 (0.41) | ALKALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL17661359 | 0.87 | ALK (0.49) | ALKSIRT2SIRT1ALDH1A1CYP3A4 | |
| SCHEMBL18977143 | 0.86 | KDM4E (0.36) | ALKSIRT2SIRT1ALDH1A1CYP3A4 | |
| SCHEMBL5202759 | 0.86 | NPSR1 (0.41) | ALKMAPTNPSR1L3MBTL1PTGER4 | |
| SCHEMBL17661457 | 0.85 | ALK (0.47) | ALKSIRT2SIRT1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195422-B1 | THIN FILM EL DEVICE | PANASONIC CORP (JP) | 2011-07-27 | — | — | EP | disclosed |