Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 7/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455670 | 1.00 | — | — | |
| SCHEMBL29320 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| Dodecyl Methyl Sulfoxide SCHEMBL313076 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL29144 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL7864589 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL5074212 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL224939 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL8587009 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL160437 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS | |
| SCHEMBL5294900 | 1.00 | TSHR (0.47) | TSHRTHRBCES2CES1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883488-B2 | Transdermal local anesthetic patch with injection port | SHANTHA TOTADA R | 2011-02-08 | — | — | US | claimed |
| US-7883487-B2 | Transdermal local anesthetic patch with injection port | SHANTHA TOTADA R | 2011-02-08 | — | — | US | claimed |
| WO-2010005680-A2 | TRANSDERMAL LOCAL ANESTHETIC PATCH WITH INJECTION PORT | SHANTHA TOTADA (US) | 2010-01-14 | — | — | WO | claimed |
| US-20090311311-A1 | TRANSDERMAL LOCAL ANESTHETIC PATCH WITH INJECTION PORT | SHANTHA TOTADA R | 2009-12-17 | — | — | US | claimed |
| US-20090312706-A1 | TRANSDERMAL LOCAL ANESTHETIC PATCH WITH INJECTION PORT | SHANTHA TOTADA | 2009-12-17 | — | — | US | claimed |
| US-4150114-A | ENHANCED PENETRATION | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4148893-A | SUGAR ESTER AND DIALKYL SULFOXIDE ENHANCE PENETRATION THROUGH SKIN | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4148924-A | Dermatological compositions | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4148887-A | SUGAR ESTER WITH A METHYL SULFOXIDE | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4148917-A | PENETRATION | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4148874-A | ENHANCE PENETRATION OF PHARMOCOLOGICALLY ACTIVE AGENTS THROUGH THE SKIN | THE PROCTER & GAMBLE COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4130643-A | STEROID, SUCROSE ESTER, SULFOXIDE | THE PROCTER & GAMBLE COMPANY (US) | 1978-12-19 | — | — | US | claimed |
| US-3953599-A | ANTICHOLINERGIC SCOPOLAMINE ESTERS | THE PROCTER & GAMBLE COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| US-3952099-A | MICROBIOCIDE, SUGAR ESTER, SULFOXIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-04-20 | — | — | US | claimed |
| US-20250360148-A1 | SOLID DISPERSIONS OF PSILOCYBIN | CYBIN IRL LIMITED (IE) | 2025-11-27 | — | — | US | disclosed |
| US-20250236589-A1 | THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2025-07-24 | — | — | US | disclosed |
| EP-4581013-A1 | TRYPTAMINE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Cybin IRL Limited (IE) | 2025-07-09 | — | — | EP | disclosed |
| US-4046886-A | SUGAR ESTER, PHOSPHINE OXIDE | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3953599-A | ANTICHOLINERGIC SCOPOLAMINE ESTERS | THE PROCTER & GAMBLE COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3952099-A | MICROBIOCIDE, SUGAR ESTER, SULFOXIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236589-A1 | THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE | PNMT, HTR2C, HTR2A | TSHR 631/4885THRB 422/4885CES2 119/4885 |
| US-20250360148-A1 | SOLID DISPERSIONS OF PSILOCYBIN | HTR2B, HTR2A, HTR2C | TSHR 2857/4885THRB 3331/4885CES2 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.