Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15601866 | 0.83 | PMP22 (0.64) | PMP22 | |
| SCHEMBL14608893 | 0.83 | PMP22 (0.64) | PMP22 | |
| SCHEMBL7805773 | 0.82 | NLRP3 (0.36) | PMP22 | |
| SCHEMBL15339726 | 0.82 | NLRP3 (0.36) | PMP22 | |
| SCHEMBL10001780 | 0.78 | PMP22 (0.70) | PMP22 | |
| SCHEMBL10001779 | 0.78 | PMP22 (0.70) | PMP22 | |
| SCHEMBL19958496 | 0.74 | — | — | |
| SCHEMBL13410354 | 0.72 | GABRR1 (0.46) | — | |
| SCHEMBL15592489 | 0.71 | PMP22 (0.60) | PMP22 | |
| SCHEMBL14089773 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020130151-A1 | Novel activity-based probes for neutrophil elastase and their use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-06-25 | — | — | WO | disclosed |