Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.62 |
| ▸ | BRD4 | O60885 | 15/20 | 0.53 |
| ▸ | TAF1 | P21675 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455928 | 0.88 | BRD9 (0.56) | BRD9BRD4TAF1 | |
| SCHEMBL22137540 | 0.88 | BRD9 (0.56) | BRD9BRD4TAF1 | |
| SCHEMBL22137661 | 0.88 | BRD9 (0.56) | BRD9BRD4TAF1 | |
| SCHEMBL22137632 | 0.87 | BRD9 (0.55) | BRD9BRD4TAF1 | |
| SCHEMBL29455902 | 0.87 | BRD9 (0.60) | BRD9BRD4TAF1 | |
| SCHEMBL22137662 | 0.87 | BRD9 (0.60) | BRD9BRD4TAF1 | |
| SCHEMBL29455950 | 0.86 | BRD9 (0.54) | BRD9BRD4TAF1 | |
| SCHEMBL22137538 | 0.86 | BRD9 (0.54) | BRD9BRD4TAF1 | |
| SCHEMBL22137539 | 0.84 | BRD9 (0.52) | BRD9BRD4TAF1 | |
| SCHEMBL22137542 | 0.84 | BRD4 (0.52) | BRD9BRD4TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636290-B2 | BET inhibitors for modulating DUX4 expression in FSHD | SAINT LOUIS UNIVERSITY (US) | 2026-05-26 | — | — | US | disclosed |
| US-20220079951-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | SAINT LOUIS UNIVERSITY (US) | 2022-03-17 | — | — | US | disclosed |
| WO-2020132004-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | SAINT LOUIS UNIVERSITY (US) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220079951-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | BRDT, PHKB, BET1 | BRD9 15/4885BRD4 4/4885TAF1 23/4885 |
| US-12636290-B2 | BET inhibitors for modulating DUX4 expression in FSHD | BRDT, BET1, PHKB | BRD9 22/4885BRD4 6/4885TAF1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.