Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.40 |
| ▸ | CHRNG | P07510 | 2/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.40 |
| ▸ | CHRND | Q07001 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 8/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22138373 | 0.92 | FURIN (0.45) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL22138449 | 0.92 | SIRT1 (0.41) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL24829575 | 0.92 | SIRT1 (0.41) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL25733655 | 0.91 | FURIN (0.45) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL24916488 | 0.91 | FURIN (0.48) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL19591557 | 0.91 | FURIN (0.49) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL22702532 | 0.90 | FURIN (0.38) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL24591729 | 0.90 | GLP1R (0.39) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL22702633 | 0.88 | TRPV1 (0.38) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL14012350 | 0.87 | HTT (0.38) | FURINHTTGLP1RSIRT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211984-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
| WO-2020132483-A1 | RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |