Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | NPY4R | P50391 | 6/20 | 0.41 |
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21569760 | 0.93 | FURIN (0.47) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL24829476 | 0.93 | FURIN (0.47) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL19591557 | 0.90 | FURIN (0.49) | FURINHTTSIRT2SIRT1 | |
| SCHEMBL14887317 | 0.89 | SIRT2 (0.43) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL18758412 | 0.88 | SIRT5 (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL17752434 | 0.88 | SIRT5 (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL22138373 | 0.88 | FURIN (0.45) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL16091795 | 0.88 | SIRT5 (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL23385514 | 0.88 | NPY5R (0.38) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL19370636 | 0.88 | SIRT5 (0.42) | FURINNPY5RNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211984-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
| WO-2020132483-A1 | RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |