Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | TTK | P33981 | 3/20 | 0.35 |
| ▸ | QPCT | Q16769 | 7/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123217 | 0.87 | PTK6 (0.48) | PTK6AURKBEGFRFGFR3ERBB2 | |
| SCHEMBL22122922 | 0.87 | PTK6 (0.43) | PTK6AURKBEGFRTTKQPCT | |
| SCHEMBL30171553 | 0.87 | PTK6 (0.43) | PTK6AURKBEGFRTTKQPCT | |
| SCHEMBL22123141 | 0.87 | TTK (0.38) | PTK6AURKBEGFRTTKFGFR3 | |
| SCHEMBL22123977 | 0.87 | PTK6 (0.44) | PTK6AURKBEGFRTTKFGFR3 | |
| SCHEMBL30171824 | 0.87 | PTK6 (0.44) | PTK6AURKBEGFRTTKFGFR3 | |
| SCHEMBL25444479 | 0.86 | PTK6 (0.42) | PTK6AURKBTTKQPCTFGFR3 | |
| Hydrochloric Acid SCHEMBL30171690 | 0.86 | PTK6 (0.43) | PTK6AURKBEGFRTTKFGFR3 | |
| SCHEMBL25013228 | 0.85 | PTK6 (0.41) | PTK6SYKAURKBTTK | |
| Trifluoroacetic Acid SCHEMBL22123238 | 0.84 | TTK (0.39) | PTK6AURKBTTKFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126954-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |