Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.42 |
| ▸ | TTK | P33981 | 5/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | QPCT | Q16769 | 5/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171553 | 0.98 | PTK6 (0.43) | PTK6TTKAURKBQPCTFGFR3 | |
| SCHEMBL22122922 | 0.98 | PTK6 (0.43) | PTK6TTKAURKBQPCTFGFR3 | |
| SCHEMBL22123977 | 0.95 | PTK6 (0.44) | PTK6TTKAURKBFGFR3PTK2 | |
| SCHEMBL30171824 | 0.95 | PTK6 (0.44) | PTK6TTKAURKBFGFR3PTK2 | |
| Hydrochloric Acid SCHEMBL30171690 | 0.95 | PTK6 (0.43) | PTK6TTKAURKBFGFR3KDM4E | |
| SCHEMBL24910483 | 0.93 | KDM4E (0.43) | TTKHTR1ADRD2DRD4DRD3 | |
| SCHEMBL22123763 | 0.92 | TTK (0.39) | PTK6TTKAURKBFGFR3KDM4E | |
| SCHEMBL30171778 | 0.92 | TTK (0.39) | PTK6TTKAURKBFGFR3KDM4E | |
| SCHEMBL30183416 | 0.91 | PTK6 (0.50) | PTK6AURKBKDM4EGAASMN1; SMN2 | |
| SCHEMBL30183403 | 0.90 | PTK6 (0.47) | PTK6TTKAURKBPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |