Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 16/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.41 |
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139158 | 0.93 | PTK6 (0.46) | PTK6AURKBIGF1RLCK | |
| SCHEMBL24910529 | 0.92 | PTK6 (0.46) | PTK6AURKBLCK | |
| SCHEMBL22139090 | 0.92 | PTK6 (0.58) | PTK6AURKBLCK | |
| SCHEMBL22124049 | 0.92 | PTK6 (0.46) | PTK6AURKBIGF1RLCK | |
| Hydrochloric Acid SCHEMBL30172053 | 0.91 | PTK6 (0.57) | PTK6AURKBLCK | |
| SCHEMBL22139138 | 0.91 | PTK6 (0.45) | PTK6AURKBIGF1RLCKFGFR3 | |
| SCHEMBL22139132 | 0.90 | PTK6 (0.45) | PTK6AURKBLCK | |
| SCHEMBL22123982 | 0.90 | PTK6 (0.44) | PTK6AURKBLCK | |
| SCHEMBL22124309 | 0.90 | PTK6 (0.51) | PTK6AURKBLCK | |
| SCHEMBL30177684 | 0.90 | PTK6 (0.51) | PTK6AURKBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126954-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |