Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170317 | 0.94 | PTK6 (0.46) | PTK6AURKBMAPKAPK5LCKSYK | |
| SCHEMBL22139237 | 0.93 | PTK6 (0.48) | PTK6AURKBLCKIGF1R | |
| SCHEMBL25444811 | 0.92 | PTK6 (0.44) | PTK6AURKBMAPKAPK5LCKSYK | |
| SCHEMBL22124899 | 0.92 | PTK6 (0.56) | PTK6AURKBLCKTTK | |
| SCHEMBL24112364 | 0.92 | PTK6 (0.56) | PTK6AURKBLCK | |
| SCHEMBL30177799 | 0.92 | PTK6 (0.56) | PTK6AURKBLCKTTK | |
| SCHEMBL30178012 | 0.91 | PTK6 (0.44) | PTK6AURKBMAPKAPK5LCKSYK | |
| Hydrochloric Acid SCHEMBL25173591 | 0.91 | PTK6 (0.55) | PTK6AURKBLCKTTK | |
| SCHEMBL22124402 | 0.91 | PTK6 (0.54) | PTK6AURKBLCK | |
| SCHEMBL24916505 | 0.91 | PTK6 (0.43) | PTK6AURKBMAPKAPK5LCKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126954-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |