⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23655011 | 0.76 | DPP4 (0.30) | — | |
| SCHEMBL5847294 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL29180799 | 0.74 | — | — | |
| SCHEMBL19225209 | 0.73 | FFAR2 (0.33) | — | |
| SCHEMBL8260827 | 0.73 | — | — | |
| SCHEMBL6850696 | 0.73 | — | — | |
| SCHEMBL8260376 | 0.73 | — | — | |
| SCHEMBL8677957 | 0.72 | — | — | |
| SCHEMBL18102339 | 0.72 | — | — | |
| SCHEMBL13183900 | 0.72 | CACNA1B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021250194-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2021-12-16 | — | — | WO | disclosed |
| WO-2020127685-A1 | AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2020-06-25 | — | — | WO | disclosed |