⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594598 | 0.80 | MAPK1 (0.51) | — | |
| SCHEMBL257500 | 0.73 | — | — | |
| SCHEMBL23010482 | 0.71 | — | — | |
| SCHEMBL17149930 | 0.71 | — | — | |
| SCHEMBL20660494 | 0.69 | MAPK1 (0.38) | — | |
| SCHEMBL21626155 | 0.69 | F2 (0.43) | — | |
| SCHEMBL20660821 | 0.68 | ALDH1A1 (0.36) | — | |
| SCHEMBL15043736 | 0.68 | MAPK1 (0.47) | — | |
| SCHEMBL2935690 | 0.68 | — | — | |
| SCHEMBL293389 | 0.67 | MAPK1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670186-B | Pyrazolopyridine-diamides, their use as pesticides and process for their preparation | PI工业有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-111670186-B | Pyrazolopyridine-diamides, their use as pesticides and process for their preparation | PI工业有限公司 | 2023-10-17 | — | — | CN | disclosed |
| US-11377425-B1 | Small molecule modulators of IL-17 | LEO PHARMA A/S (DK) | 2022-07-05 | — | — | US | disclosed |
| WO-2020127685-A1 | AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2020-06-25 | — | — | WO | disclosed |