SCHEMBL22143757

SCHEMBL22143757

C=COc1ccc(C(=O)Oc2ccc(OC(=O)C3CCC(OC)CC3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 2/20 0.46
▸ KMT2A Q03164 3/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ POLB P06746 1/20 0.40
▸ HPGD P15428 4/20 0.40
▸ MAPT P10636 2/20 0.38
▸ GFER P55789 1/20 0.38
▸ LMNA P02545 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ ACR P10323 2/20 0.35
▸ HGFAC Q04756 1/20 0.35
▸ PRSS1 P07477 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20852356 0.86 ELANE (0.51) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL12509996 0.85 ELANE (0.50) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL19577866 0.82 KMT2A (0.52) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16451644 0.81 ELANE (0.40) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16557883 0.81 ELANE (0.40) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16557882 0.80 ELANE (0.39) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL22543451 0.79 HTT (0.50) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL14192384 0.79 ELANE (0.47) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL19513531 0.78 ELANE (0.51) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL19431475 0.78 ELANE (0.51) ELANEKMT2ASMN1; SMN2HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11243343-B2 Backlight unit and liquid crystal display device FUJIFILM CORPORATION (JP) 2022-02-08 — — US disclosed
US-20200200961-A1 BACKLIGHT UNIT AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-06-25 — — US disclosed
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