SCHEMBL16557883

SCHEMBL16557883

C=CC(=O)OCOc1ccc(OC(=O)c2ccc(OC(=O)C3CCC(OC)CC3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.40
KMT2A Q03164 4/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 2/20 0.36
CCNC P24863 1/20 0.34
CDK8 P49336 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 3/20 0.33
THRB P10828 2/20 0.33
HPGD P15428 1/20 0.33
GFER P55789 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PRSS1 P07477 1/20 0.33
ACR P10323 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16451644 1.00 ELANE (0.40) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL10000345 0.94 KMT2A (0.42) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL16557882 0.91 ELANE (0.39) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL16449858 0.91 ELANE (0.41) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL16449846 0.89 ELANE (0.41) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL16449849 0.89 ELANE (0.41) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL22580209 0.85 KMT2A (0.50) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL15397343 0.85 KMT2A (0.50) ELANEKMT2AHTTSMN1; SMN2TDP1
SCHEMBL19930179 0.85 NPC1 (0.44) KMT2ASMN1; SMN2POLBMEN1MAPT
SCHEMBL10000377 0.84 SMN1; SMN2 (0.44) ELANEKMT2AHTTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150070764-A1 METHOD FOR PRODUCING LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-12 US disclosed