Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22143936 | 0.91 | DDB1 (0.44) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL22143893 | 0.89 | SCN9A (0.43) | DDB1CRBNKMT2ASCN9ACTSL | |
| SCHEMBL22143891 | 0.89 | DDB1 (0.45) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL22144163 | 0.87 | CYP3A4 (0.44) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL22143894 | 0.84 | DDB1 (0.49) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL22143928 | 0.84 | DDB1 (0.44) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL22143937 | 0.82 | DDB1 (0.47) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL29360415 | 0.81 | DDB1 (0.44) | DDB1CRBNSCN9ASTAT3 | |
| SCHEMBL22143927 | 0.80 | DDB1 (0.45) | DDB1CRBNTNFIL1BTBXA2R | |
| SCHEMBL22313070 | 0.80 | DDB1 (0.45) | DDB1CRBNTNFIL1BTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199097-A1 | POMALIDOMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR | NANJING NORATECH PHARMACEUTICALS CO., LTD (CN) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199097-A1 | POMALIDOMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR | WEE2, WEE1, HASPIN | DDB1 4324/4885CRBN 3676/4885TNF 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.