Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144486 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL22144688 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL2301088 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL9616068 | 0.75 | TSHR (0.47) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL21893768 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL2823070 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL20851163 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL18161341 | 0.72 | HSD17B10 (0.57) | KDM4EALDH1A1GAAGLANPC1 | |
| SCHEMBL17479668 | 0.71 | GAA (0.49) | KDM4EALDH1A1GAANPC1HSD17B10 | |
| SCHEMBL11357473 | 0.70 | KMT2A (0.56) | KDM4EALDH1A1GAAGLANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |