Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696695 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL2639846 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL21299170 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL16889011 | 0.75 | — | — | |
| SCHEMBL20279044 | 0.72 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL13624897 | 0.72 | DPP4 (0.36) | DPP4DPP8DPP9SLC6A3OPRD1 | |
| SCHEMBL7964213 | 0.72 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL19143537 | 0.72 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL7964218 | 0.72 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL19214802 | 0.72 | DPP4 (0.36) | DPP4DPP8DPP9SLC6A3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2020132588-A1 | COMBINATION THERAPY OF ARMS AND NATURAL KILLER CELLS | KLEO PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |