Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696695 | 1.00 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL2639846 | 1.00 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL22144945 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL16297957 | 0.78 | SLC6A3 (0.41) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL13342875 | 0.75 | — | — | |
| SCHEMBL16889011 | 0.75 | — | — | |
| SCHEMBL13342874 | 0.75 | — | — | |
| SCHEMBL2639842 | 0.74 | DPP4 (0.41) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL1696692 | 0.74 | DPP4 (0.41) | DPP4DPP8DPP9SLC6A3CAPN1 | |
| SCHEMBL1696690 | 0.74 | DPP4 (0.41) | DPP4DPP8DPP9SLC6A3CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229138-B1 | TOPICAL COMPOSITIONS COMPRISING NON-PROTEOGENIC AMINO ACIDS AND METHODS OF TREATING SKIN | AVON PROD INC (US) | 2019-08-28 | — | — | EP | disclosed |