SCHEMBL221465

SCHEMBL221465

N#Cc1ccc(N)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729202 1.00
SCHEMBL5140739 1.00 PIK3CD (0.47)
SCHEMBL15156799 0.83 PIK3CD (0.59)
SCHEMBL4480751 0.78 CYP19A1 (0.56)
SCHEMBL3955808 0.77 PIK3CD (0.38)
SCHEMBL3955805 0.77 PIK3CD (0.38)
SCHEMBL22495356 0.76 GPR119 (0.51)
SCHEMBL2445812 0.76
SCHEMBL1146143 0.76
SCHEMBL503142 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118086841-B TiSiNiYN coating for enhancing high-temperature wear resistance 纳狮新材料有限公司杭州分公司 2025-02-07 CN claimed
US-20240154124-A1 NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO., LTD. (CN) 2024-05-09 US claimed
CN-116354900-B Chlorothiazole compound containing maleic acid structure, and preparation method and application thereof 中国农业大学 2024-03-12 CN claimed
CN-116354900-A Chlorothiazole compound containing maleic acid structure, and preparation method and application thereof 中国农业大学 2023-06-30 CN claimed
CN-115210339-A Etching solution for titanium nitride and molybdenum conductive metal wires 弗萨姆材料美国有限责任公司 2022-10-18 CN claimed
EP-2507243-B1 SPIROINDOLINONE PYRROLIDINES HOFFMANN LA ROCHE (CH) 2015-06-10 EP claimed
EP-2507243-A1 SPIROINDOLINONE PYRROLIDINES F. Hoffmann-La Roche AG (CH) 2012-10-10 EP claimed
US-20110312935-A1 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-12-22 US claimed
EP-1648874-B1 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2011-10-05 EP claimed
EP-1846035-B1 COMBINATION THERAPY XENON PHARMACEUTICALS INC (CA) 2011-09-21 EP claimed
US-6326359-B1 PURINE DERIVATIVES PFIZER INC 2001-12-04 US claimed
EP-1121372-A1 ADENINE DERIVATIVES Pfizer Limited (GB) 2001-08-08 EP claimed
WO-2000023457-A1 ADENINE DERIVATIVES PFIZER LIMITED (GB) 2000-04-27 WO claimed
EP-0607803-B1 Process for the preparation of 6-amino-3-pyridinecarbonitriles BAYER AG (DE) 1996-07-10 EP claimed
EP-0596491-B1 Method for halogenating an aromatic compound ISHIHARA SANGYO KAISHA (JP) 1996-07-10 EP claimed
US-5491239-A Method for halogenating an aromatic compound ISHIHARA SANGYO KAISHA LTD. (JP) 1996-02-13 US claimed
EP-0596491-A1 Method for halogenating an aromatic compound ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-05-11 EP claimed
EP-0181636-B1 2 5-CYANOPYRIDINE-2-DIAZOHYDROXIDE, BASIC SALTS AND METHODS FOR PRODUCTION AND USE UNIV ALABAMA (US) 1990-02-28 EP claimed
EP-0181636-A2 2 5-Cyanopyridine-2-diazohydroxide, basic salts and methods for production and use THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 1986-05-21 EP claimed
US-4141977-A Treatment of psoriasis with 6-substituted nicotinamides, 2-substituted pyrazinamides and closely related compounds YU RUEY J 1979-02-27 US claimed