Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146493 | 0.84 | CHRNB2 (0.43) | ALDH1A1MAPK1KDM4EHSD17B10CHRNB2 | |
| SCHEMBL9534277 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL24131737 | 0.75 | TSHR (0.52) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL965401 | 0.74 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL22146749 | 0.72 | CHRNB2 (0.46) | ALDH1A1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8381807 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL12116102 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL603785 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4611409 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL603784 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200197409-A1 | HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO., LTD. (CN) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200197409-A1 | HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR | HAVCR2, CD74, HLA-B | SMN1; SMN2 4656/4885ALDH1A1 1143/4885LMNA 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.