Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146692 | 0.98 | ALOX5 (0.45) | ALOX5ESR1ESR2GGPS1PRKDC | |
| SCHEMBL440590 | 0.91 | ALOX5 (0.47) | ALOX5ESR1ESR2GGPS1PRKDC | |
| SCHEMBL21742672 | 0.91 | ALOX5 (0.52) | ALOX5GGPS1PRKDCPDK2LMNA | |
| SCHEMBL9917134 | 0.91 | ALOX5 (0.52) | ALOX5GGPS1PRKDCPDK2LMNA | |
| SCHEMBL437623 | 0.89 | ALOX5 (0.54) | ALOX5ESR1ESR2GGPS1PRKDC | |
| SCHEMBL16182135 | 0.88 | ALOX5 (0.52) | ALOX5ESR1ESR2GGPS1PRKDC | |
| SCHEMBL438642 | 0.88 | ALOX5 (0.52) | ALOX5ESR1ESR2GGPS1PRKDC | |
| SCHEMBL24434074 | 0.87 | ALOX5 (0.40) | ALOX5GGPS1PRKDCPDK2MAOB | |
| SCHEMBL438618 | 0.86 | ALOX5 (0.51) | ALOX5ESR1ESR2GGPS1PRKDC | |
| SCHEMBL371292 | 0.86 | ALOX5 (0.51) | ALOX5ESR1ESR2GGPS1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127259-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |