Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12996616 | 0.89 | ALOX5 (0.60) | ALOX5KMT2AMAPTSMN1; SMN2GGPS1 | |
| SCHEMBL22146688 | 0.87 | ALOX5 (0.57) | ALOX5MEN1KMT2AMAPTGGPS1 | |
| SCHEMBL29572393 | 0.87 | ALOX5 (0.57) | ALOX5MEN1KMT2AMAPTGGPS1 | |
| SCHEMBL22146711 | 0.85 | ALOX5 (0.56) | ALOX5MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL24742449 | 0.85 | ALOX5 (0.53) | ALOX5GGPS1HDAC8HDAC6NPC1 | |
| SCHEMBL22146815 | 0.84 | ALOX5 (0.51) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22146812 | 0.83 | ALOX5 (0.53) | ALOX5MAPTMAPK1GGPS1L3MBTL1 | |
| SCHEMBL17167457 | 0.83 | ALOX5 (0.58) | ALOX5GGPS1NPC1RAB9APRKDC | |
| SCHEMBL18086162 | 0.82 | ALOX5 (0.66) | ALOX5GGPS1HDAC8NPC1RAB9A | |
| SCHEMBL12996620 | 0.81 | ALOX5 (0.61) | ALOX5KMT2AMAPTGGPS1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| US-20220109116-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-04-07 | — | — | US | disclosed |
| WO-2020127259-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127176-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220109116-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | ALOX5 3331/4885MEN1 1245/4885KMT2A 1528/4885 |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | ALOX5 3331/4885MEN1 1245/4885KMT2A 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.