Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | APP | P05067 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146913 | 1.00 | MAPT (0.77) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| SCHEMBL403374 | 0.98 | MAPT (0.81) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| SCHEMBL22146845 | 0.90 | APP (0.72) | MAPTAPPTSHRCYP3A4HSD17B10 | |
| SCHEMBL1009236 | 0.87 | MAPT (1.00) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| SCHEMBL9611197 | 0.87 | APP (0.77) | MAPTAPPTSHRCYP3A4HSD17B10 | |
| SCHEMBL9121457 | 0.84 | APP (0.69) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| SCHEMBL17312253 | 0.82 | APP (0.73) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| SCHEMBL30495998 | 0.82 | APP (0.73) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| Benzene SCHEMBL28733255 | 0.82 | APP (0.73) | MAPTAPPTSHRCYP3A4CYP1A2 | |
| SCHEMBL403663 | 0.82 | APP (0.73) | MAPTAPPTSHRCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199657-A1 | OPTICAL SUPER-MULTIPLEXING BY POLYYNES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2020-06-25 | — | — | US | disclosed |