SCHEMBL1009236

SCHEMBL1009236

Nc1ccc(C#Cc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 1.00
▸ APP P05067 4/20 0.78
▸ CYP3A4 P08684 3/20 0.56
▸ CYP1A2 P05177 3/20 0.56
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ CYP2C9 P11712 2/20 0.56
▸ CYP2C19 P33261 2/20 0.56
▸ NPC1 O15118 2/20 0.56
▸ KDM4E B2RXH2 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ TSHR P16473 1/20 0.53
▸ CA12 O43570 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ TAAR1 Q96RJ0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL403374 0.90 MAPT (0.81) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL864945 0.88 APP (1.00) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL9611200 0.88 APP (1.00) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL22146913 0.87 MAPT (0.77) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL22147223 0.87 MAPT (0.77) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL18334296 0.87 MAPT (0.75) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL2114741 0.85 APP (0.92) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL13717014 0.84 MAPT (0.73) MAPTAPPCYP3A4CYP1A2MEN1
SCHEMBL5744049 0.83 MAPT (0.69) MAPTAPPMEN1KMT2ANPC1
SCHEMBL21903463 0.82 APP (0.88) MAPTAPPCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415892-B2 Polyimide film preparation method and application thereof INSTITUTE OF CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2025-09-16 — — US claimed
CN-119613720-A Polyimide slurry for flexible display substrate, preparation method of polyimide slurry and preparation method of polyimide film 苏州聚萃材料科技有限公司 2025-03-14 — — CN claimed
WO-2024216910-A1 HIGH-CHEMICAL-RESISTANCE POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 明士(北京)新材料开发有限公司 2024-10-24 — — WO claimed
CN-117555204-B Negative photosensitive polyimide glue solution and glue film suitable for flexible circuit board 明士(北京)新材料开发有限公司 2024-04-26 — — CN claimed
CN-117430812-B Photosensitive polyamic acid ester resin, resin composition and application 明士(北京)新材料开发有限公司 2024-03-19 — — CN claimed
CN-114685787-B Polyimide film with synergistic crosslinking structure and preparation method and application thereof 上海市塑料研究所有限公司 2024-03-08 — — CN claimed
CN-117555204-A Negative photosensitive polyimide glue solution and glue film suitable for flexible circuit board 明士(北京)新材料开发有限公司 2024-02-13 — — CN claimed
CN-117430812-A Photosensitive polyamic acid ester resin, resin composition and application 明士(北京)新材料开发有限公司 2024-01-23 — — CN claimed
CN-117384378-A Photosensitive polyamic acid ester resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2024-01-12 — — CN claimed
CN-117209758-A Preparation method of thermosetting polyimide material 万华化学集团股份有限公司 2023-12-12 — — CN claimed
CN-112980014-A Blended polyimide film, preparation method thereof and application thereof in flexible display substrate 上海市合成树脂研究所有限公司 2021-06-18 — — CN claimed
WO-2020200229-A1 POLYIMIDE THIN FILM AND PREPARATION METHOD AND APPLICATION THEREOF 中国科学院化学研究所 2020-10-08 — — WO claimed
EP-2404948-B1 OXYGEN-ABSORBABLE SOLVENT-SOLUBLE RESIN AND OXYGEN-ABSORBABLE ADHESIVE RESIN COMPOSITION TOYO SEIKAN KAISHA LTD (JP) 2016-08-24 — — EP claimed
EP-1458791-B1 METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S GEN ELECTRIC (US) 2006-11-29 — — EP claimed
EP-0808852-B1 Low chlorine polyalkylene substituted carboxylic acylating agent compositions and compounds derived therefrom LUBRIZOL CORP (US) 2003-12-17 — — EP claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 — — US claimed
EP-0330219-B1 Preparation of substituted phthalic anhydride OCCIDENTAL CHEM CO (US) 1993-12-29 — — EP claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 — — US claimed
EP-0004405-B1 PROCESS FOR THE FORMATION OF HIGH-PURITY TETRAHYDROPHTHALIC ACID ANHYDRIDE CHEMISCHE WERKE HÜLS AG (DE) 1981-11-25 — — EP claimed
EP-0004405-A2 Process for the formation of high-purity tetrahydrophthalic acid anhydride CHEMISCHE WERKE HÜLS AG (DE) 1979-10-03 — — EP claimed
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