Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.30 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21695211 | 0.90 | CHRM5 (0.50) | CHRM3CHRM5SIGMAR1SMN1; SMN2CYP3A4 | |
| SCHEMBL20179968 | 0.90 | CHRM5 (0.50) | CHRM3CHRM5SIGMAR1SMN1; SMN2CYP3A4 | |
| SCHEMBL21946897 | 0.89 | CHRM5 (0.51) | CHRM3CHRM5SIGMAR1SMN1; SMN2CYP3A4 | |
| SCHEMBL583320 | 0.87 | SIGMAR1 (0.49) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 | |
| SCHEMBL1149470 | 0.87 | SIGMAR1 (0.49) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 | |
| SCHEMBL4771744 | 0.85 | SIGMAR1 (0.47) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 | |
| Bromide SCHEMBL583318 | 0.85 | SIGMAR1 (0.47) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 | |
| Hydrochloric Acid SCHEMBL8209880 | 0.85 | SIGMAR1 (0.47) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 | |
| SCHEMBL649131 | 0.85 | SIGMAR1 (0.50) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 | |
| SCHEMBL4134315 | 0.85 | SIGMAR1 (0.50) | CHRM3CHRM5SIGMAR1PLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541368-B1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | US HEALTH (US) | 2023-07-12 | — | — | EP | disclosed |
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) | 2022-07-12 | — | — | US | disclosed |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | PUF60, PBRM1, PCBP1 | CHRM3 4100/4885CHRM5 4484/4885SIGMAR1 1647/4885 |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | PUF60, PBRM1, PCBP1 | CHRM3 4100/4885CHRM5 4484/4885SIGMAR1 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.