SCHEMBL22147865

SCHEMBL22147865

Cc1cc(-c2ncc(CC(N)=O)cc2C)ccn1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
WNT3A P56704 19/20 0.58
PORCN Q9H237 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12302667 0.88 WNT3A (0.61) WNT3APORCN
SCHEMBL3711598 0.87 WNT3A (0.52) WNT3APORCN
SCHEMBL22148303 0.84 WNT3A (0.59) WNT3APORCN
SCHEMBL30479192 0.84 WNT3A (0.64) WNT3APORCN
SCHEMBL29309899 0.82 WNT3A (0.54) WNT3APORCN
SCHEMBL1912413 0.81 WNT3A (0.52) WNT3APORCN
SCHEMBL12302714 0.81 WNT3A (0.53) WNT3APORCN
Hydrochloric Acid SCHEMBL249352 0.80 WNT3A (0.51) WNT3APORCN
SCHEMBL22148134 0.80 WNT3A (0.53) WNT3APORCN
SCHEMBL22147858 0.80 WNT3A (0.54) WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020125759-A1 COMPOUND AS WNT SIGNAL PATHWAY INHIBITOR AND MEDICAL USE THEREOF 汇瀚医疗科技有限公司 2020-06-25 WO disclosed