Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220957 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CXCR4KDM4EKMT2A | |
| SCHEMBL18760224 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNACPB2CXCR4EPHX2 | |
| SCHEMBL18786157 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNACPB2CXCR4EPHX2 | |
| SCHEMBL22054640 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1CXCR4KDM4EKMT2A | |
| SCHEMBL20792784 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1CXCR4KDM4EKMT2A | |
| SCHEMBL2263297 | 0.74 | GSR (0.46) | SMN1; SMN2ALDH1A1CXCR4KDM4E | |
| SCHEMBL2263302 | 0.74 | GSR (0.46) | SMN1; SMN2ALDH1A1CXCR4KDM4E | |
| SCHEMBL24437738 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1CXCR4KDM4EGAA | |
| SCHEMBL23451044 | 0.73 | FOLH1 (0.51) | CPB2 | |
| SCHEMBL5419504 | 0.73 | FOLH1 (0.51) | CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199177-A1 | Dual-Enzyme Responsive Peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199177-A1 | Dual-Enzyme Responsive Peptides | DNPEP, PEPD, APEH | SMN1; SMN2 4488/4885LMNA 3516/4885CPB2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.